Berberine, primarily extracted from Berberis Aristata, is an alkaloid known for its beneficial properties, ranging from the control of glucose and lipid metabolism to the promotion of cardiovascular and gastrointestinal health. Despite its remarkable benefits, berberine presents challenges such as its unpleasant taste and poor bioavailability, which limit its effectiveness as a dietary supplement.
Benefits of Berberine
Berberine is effective in regulating blood glucose levels, significantly contributing to the management of type 2 diabetes. Additionally, thanks to its antibacterial and anti-inflammatory properties, it is used in the treatment of digestive disorders and to improve cardiovascular health by reducing LDL cholesterol.
Berberine MINIACTIVES® TM: An Innovative Solution by IPS
To overcome the limitations related to taste and absorption of berberine, IPS International Products & Services S.r.l. has developed Berberine MINIACTIVES® TM (Taste Masking). This advanced formulation not only effectively masks the bitter taste of berberine but also enhances its absorption profile thanks to MINIACTIVES® technology. This granular coating-based technology allows berberine to be optimally absorbed in the intestine, thus maximizing its therapeutic effects without discomfort to the patient.
Studies and Scientific Collaborations
IPS actively collaborates with academic institutions and specialized laboratories in preclinical studies to validate the efficacy and safety of its technologies used in the production of a wide range of nutraceutical ingredients. Recently, studies on 3D organoid systems have delved into the effectiveness of IPS technologies, analyzing the action of various nutraceutical ingredients created with them. The results highlight a significant decrease in levels of inflammation and gastric and intestinal sensitivity, compared to standard ingredients. Additionally, improved absorption was observed, which enhances the therapeutic properties, such as the anti-inflammatory and antioxidant actions, of the analyzed ingredients.
Formulations and Applications
Berberine MINIACTIVES® TM is suitable for creating various dosage forms, such as tablets, sachets, stick packs, capsules, and vials with dosing caps, offering a wide range of options for dietary supplements. For applications requiring direct compression, IPS also offers SmarTTabs®, custom formulations that preserve the original release profile of the actives, ensuring the integrity and effectiveness of the active ingredient.
Conclusion
With Berberine MINIACTIVES® TM, IPS introduces an advanced nutraceutical solution that overcomes the traditional challenges associated with the use of berberine. Continuous innovation and a science-based approach affirm IPS’s role as a leader in the nutraceutical industry, providing cutting-edge products that effectively meet the needs of the modern market.
Note: This article is provided for informational purposes only and does not substitute for professional medical advice.
